Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis
نویسندگان
چکیده
منابع مشابه
Genetic susceptibility to atopic dermatitis.
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with an increasing prevalence in industrialized countries. AD belongs to the group of allergic disorders that includes food allergy, allergic rhinitis, and asthma. A multifactorial background for AD has been suggested, with genetic as well as environmental factors influencing disease development. Recent breakthroughs in genetic meth...
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Atopic dermatitis is a heterogeneous, chronic, and inflammatory skin disease that is associated with a profound symptom burden. Recent studies have demonstrated associations between atopic dermatitis and a number of multi-organ and systemic disorders. The origin of these comorbid conditions is likely multifactorial, with combined effects of skin-barrier disruption, immune dysregulation, intense...
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ژورنال
عنوان ژورنال: BMC Medical Genetics
سال: 2012
ISSN: 1471-2350
DOI: 10.1186/1471-2350-13-8